Ulcer disease, ulcer, ulcer or ulcer is limited linear damage the lining of the stomach and duodenum. This damage penetrating the muscle layer of the lining of the serous layer, and occurs under the action of acid and pepsin HCl
This "boil" occurs in parts of the digestive system where there is activity of gastric acid and pepsin - the esophagus, stomach, duodenum, and part of the small intestine. Ulcers (ulcers) heal the scar.
Ulcer disease occurs when a disturbed balance between defensive and aggressive factors. The defense factors include: the natural resistance of the mucous membrane of the stomach and duodenum, gastric mucus (mucus), blood circulation in the mucosa, gastric bicarbonate secretion and recovery of cells after mucosal damage.Aggressive factors include: hlorovodikova acid and pepsin.
Although it has its own distinct epidemiological specificity of ulcer disease is the mass in the group can svrstasti chronic multifactorial diseases such as diabetes, hypertension, or chronic obstructive pulmonary disease.
Ulcer of the stomach and duodenum is multifactorial chronic disease in its creation are present:
First major risk factors: Helicobacter pylori is present in 85-100 percent of duodenal ulcers and 70 percent of gastric ulcers, the use of NSAIDs and stress and
Second minor risk factors: excessive secretion of gastric acid, viral infection, vascular insufficiency associated with cardiorespiratory disease and diseases of the liver and pancreas, genetic predisposition, stress, alcohol and smoking.
Nicotine is the most powerful organ toxicant, the main ingredient in cigarettes, along with carbon monoxide and carbon dioxide released during the dry distillation. Children who smoke in the development, during the life they have problems with eyesight, hearing and intelligence.
Nicotine acts on the nerves and blood vessels, so that smokers are less anxious than non-smokers. The skin of smokers, both men and women, look older by ten years compared to non-smokers!
It is proved that every cigarette increases blood pressure and keep it in the pathological values of twenty minutes!In many clinical and experimental studies established the close connection between smoking and ulcer disease.
Smoking slows healing of ulcers and impact on recurrence, increases the risk of complications and mortality, probably due to cardiac and pulmonary consequences of smoking, and aggressive ulcer disease.
It was noted that smoking is an important risk factor for developing ulcers, not only before and after eradication of Helicobacter pylori.
The intensity of smoking
When smoking nicotine blocks the secretion of pancreatic bicarbonate, absent hlorovodikove neutralization of acid in the duodenum, which favors the development of ulcers. Smokers have an increased risk of gastric and duodenal ulcers and is proportional to the intensity of smoking.